Cocaine is a potent central nervous system (CNS) stimulant and a local anesthetic. It is often self-administered by nasal inhalation, intravenous injection and free-base smoking.
It is excreted in urine in a short time primarily as Benzoylecgonine. Benzoylecgonine, a major metabolite of Cocaine, has a longer biological half-life (5-8 hrs) than Cocaine (0.5-1.5 hrs), and can generally be detected for 24-48 hours after Cocaine exposure.
One Step Cocaine Urine Test is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Cocaine in urine.
Test yields a positive result when Cocaine in urine reaches 300ng/ml. This is the suggested screening cut-off for positive specimens set by the substance Abuse and Mental Health Services Administration (SAMHSA, USA).
